/macport$|macport /g.test(string)

This will check for words having macport and a space appeneded or a string that ends with macport

for macports you can do the same thing by replacing macport with macports

I am on mobile so didn't check it much just check if it is working and I may have missed some cases

Do you have them in an array? That'd be ideal, as you could do something like this:

const getWords = arr => {
   const regEx = /macports?/i
   return arr.filter(x => regEx.test(x))
}

If no array, then forget about the filter, but you can still apply the same principle.

Another way to go would be:

string.includes("macport")

Though you might have to turn the string into lower case for this one.

in ruby if checking per string

 "The fastest macport".include?('macport')

Can you update the title of your post to better indicate what your issue is, so people searching may find the issue easier?